Orlistat capsule is an FDA approved weight loss supplement that is also an over-the-counter (OTC) drug. It is suitable for adults who are 18 or above.
Let us now look at how the intake of this drug affects weight management.
Orlistat for Weight Loss
Intake of this drug prevents the breakdown of dietary fats that are high in calories by blocking the activity of the lipase enzyme. Lipase enzyme is required for fat digestion. This drug blocks the intestine from absorbing about 25% of fat. The undigested fat does not get absorbed by the body and gets expelled from the body via the bowel movement. Many studies have been conducted to support the effects of this capsule.
A 2014 study published in the JAMA journal found that the long term use of this drug along with lifestyle changes may lead to greater weight loss. The drug works alongside a low-fat diet. So, if the fat intake is increased then the effects of this drug may not be the same.
It was also observed that the intake of this drug increased the rate of weight loss in obese people with no glucose tolerance or impaired glucose tolerance.
Side Effects of Orlistat
The drug blocks the breakdown of dietary fats and this can while passing through the bowel may cause gastric issues that include diarrhea and flatulence. A 2010 study showed that intake of orlistat with fatty foods may cause oily stools and anal leakage.
Further regular use of such a drug hampers the absorption of various vitamins and minerals such as vitamins E, D, A and K all of which are required for ensuring optimal health.
By having a low-fat diet one can limit the dietary intake without the side effects listed above.