Orlistat capsule is an FDA approved weight loss supplement that is also an over-the-counter (OTC) drug. It is suitable for adults who are 18 or above.
Let us now look at how the intake of this drug affects weight management.
Orlistat for Weight Loss
Intake of this drug prevents the breakdown of fats that are high in by blocking the activity of the lipase enzyme. Lipase enzyme is required for the fat digestion. This drug blocks the from absorbing about 25% of fat. The fat does not get absorbed by the body and gets expelled from the body via the bowel movement. Many studies have been conducted to support the effects of this capsule.
However, according to a 2010 research (journal: Archives of Internal Medicine) a low , keto diet led to similar improvements as orlistat therapy with a low-fat diet.
A 2014 study published in JAMA journal found that the long term use of this drug along with changes may lead to greater weight loss. The drug works alongside a low-fat diet. So, if the fat intake is increased then the effects of this drug may not be the same.
It was also observed that the intake of this drug increased the rate of weight loss in obese people with no glucose tolerance orglucose tolerance.
Side Effects of Orlistat
The drug blocks the breakdown of dietary fats and this can while passing through the bowel may cause issues that include diarrhea and flatulence. A 2010 study showed that intake of orlistat with fatty foods may cause oily stools and anal leakage.
By having a low-fat diet one can actually limit the dietary intake without the side effects listed above.