Bitter gourd has a number of important roles in human health, but in the treatment of piles, bitter gourd leaves are particularly effective. You can grind the bitter gourd leave to produce a thick juice, which can be consumed to reduce gastrointestinal inflammation and promote better digestion. Furthermore, a paste can be made of the leaves, diluted slightly with water, and applied directly to the external areas of the piles. Bitter gourd leaves are available at most specialty food stores.