Zinc & Folic Acid Ineffective As Male Infertility Treatments

by Prachee published on -

Zinc and folic acid supplements are a go-to when it comes to infertility treatments. The latest research suggests that it might not be as effective as was perceived. The new study, which aimed at studying the effect of regular folic acid and zinc supplementation on semen quality and live birth, found that it does not improve semen quality. 

The study involved 2,370 couples, out of which men were randomly assigned either daily supplements of zinc and folic acid, or placebo. Apart from no significant semen quality improvements as compared to the placebo group, the participants who received the supplements also reported gastrointestinal discomfort.

infertility treatments

Zinc and folic acid are found in several infertility treatments Photo Credit: Shutterstock

“Our study is one of the first randomized, placebo-controlled trials to assess whether folic acid and zinc supplements help to improve male fertility,” said Enrique Schisterman, Ph.D., of the NICHD Division of Intramural Population Health Research, who conducted the trial, along with colleagues. “Our results suggest that these dietary supplements have little to no effect on fertility and may even cause mild gastrointestinal symptoms.” 

Zinc is known to be a mineral essential for sperm formation, while a form of folic acid is known to aid the same. Previous studies to understand the effectiveness of these minerals in reproductive health have reported conflicting results. 

The paper has been published in JAMA. [1] [2] 

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About the Author

Prachee is a content writer for Organic Facts and is responsible for writing on the latest wellness trends. A former Journalism & Media teacher, she prides herself on being able to seamlessly dabble between health, science, and technology. She has completed her Masters in Communication Studies from the University of Pune, India as well as an online course on “Introduction to Food and Health” from Stanford University, US. Prachee fancies herself to be a poet and a cook when the rare lightning of inspiration strikes.

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