If you are at a high risk for cardiovascular disease or any other blood vessel-related condition, then cutting down your cholesterol levels is a very good idea. Cholesterol can lead to atherosclerosis, the hardening of the arteries, and will make you far more vulnerable to the negative effects of blood clots. Lean beef doesn’t contain as many of the “bad” fats that can contribute to these sorts of cardiovascular issues. Many people find it difficult to give up red meat, even after their doctors have told them about the risks to their health, but lean beef is a decent compromise to prevent blood clots.