Peppermint oil is a powerful substance that is useful in the treatment of many conditions, including migraines. Topically applying menthol oil to the temples and other inflamed areas of the head and neck can provide quick relief from migraine symptoms, including nausea, and sensitivity to light/sound. Peppermint oil possesses menthol as an active ingredient, which is an anti-inflammatory, analgesic and numbing agent, all of which can directly affect the capillaries and blood vessels near the surface of the skin.