Vanadyl Sulfate (Vanadium) Uses and Side Effects

by John Staughton (BASc, BFA) last updated -

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There are many vanadyl sulfate benefits that can help you manage diseases and improve your overall quality of life.

Vanadyl Sulfate

Vanadyl sulfate is a trace mineral found primarily in vegetable oils, soybeans, shellfish, rice, oats, and mushrooms. This mineral is needed by your body to maintain strong teeth and bones. It is marketed as a health supplement under the name vanadium. It has recently grown in popularity as a supplement marketed towards those suffering from diabetes or for bodybuilders.

Vanadyl Sulfate Uses

There are many important uses of vanadyl sulfate, including insulin control, muscle building, cholesterol reduction, bone health, tuberculosis, and prevention of cancer. Let us take a detailed look at them below.

Insulin Control

Vanadyl sulfate stimulates your cells to process glucose faster, essentially taking the place of insulin. According to a study published in the Journal of Clinical Endocrinal Metabolism, vanadyl sulfate is used as a treatment for those with metabolic disorders or for people who struggle to manage their blood sugar levels, and it may improve glucose levels by stimulating pancreatic cells and regulating their insulin production. However, other studies suggest that it does not fight insulin resistance. According to a study conducted by Dr. Meyer Halberstram et al., and published by the American Diabetes Association, this substance is not a good form of insulin control in patients who are obese. That being said, this trace mineral has been shown to be a beneficial treatment for hyperlipidemia and hypertension.

rolled oats in a wooden bowl and outside it on a wooden surface

Muscle Building

Bodybuilders and athletes will often use this mineral to boost muscle growth. Vanadyl sulfate helps muscle cells uptake more glucose, forcing more proteins and amino acids into the muscle. Because the glucose is taken in by the muscle cells instead of fat cells, it speeds the build-up of muscle mass and can help prevent fat gain.

Cholesterol Reduction

Taking vanadyl sulfate has been shown to block enzymes in the liver, leading to reduced cholesterol production, and improved cardiovascular health, with a lower risk of heart attack and stroke.

Bone Health

Vanadyl sulfate has been shown to be an essential trace mineral for bone health. In certain studies, it has been shown to promote bone cell growth. It may even help prevent fractures by strengthening bones and promoting mineralization.


In the past, this powerful substance was used as a treatment for tuberculosis and syphilis, thanks to its antimicrobial properties.

Anticancer Potential

In animal studies, vanadyl sulfate has been shown to inhibit the growth of tumor cells, and prevent the growth of new tumor cells. While the exact mechanism of its anti-cancer properties has yet to be pinned down, this trace mineral is seen as a promising cancer treatment and is currently undergoing preclinical studies.

Word of Caution

Vanadyl sulfate is considered safe in daily doses of less than 1.8mg per day. Higher doses can result in abdominal pain, nausea, and vomiting. It can also cause sluggishness and may contribute to nervous system issues. People who have been diagnosed with low blood sugar or are on medication for diabetes should use this substance cautiously, as it may reduce blood sugar and negatively interact with other medications. Prolonged use of vanadyl sulfate can result in kidney damage. Protection Status
About the Author

John Staughton is a traveling writer, editor, and publisher who earned his English and Integrative Biology degrees from the University of Illinois in Champaign, Urbana (USA). He is the co-founder of a literary journal, Sheriff Nottingham, and calls the most beautiful places in the world his office. On a perpetual journey towards the idea of home, he uses words to educate, inspire, uplift and evolve.

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