Vegetable Glycerin: Uses, Benefits, & Side Effects

by John Staughton (BASc, BFA) last updated -

Vegetable glycerin is a water-soluble sugar alcohol derived from various plant oils that can be used in a variety of cosmetic, nutritional, and medicinal applications.

What is Vegetable Glycerin?

Vegetable glycerin is widely available in a number of plant oils, such as coconut, soy, and palm oil, and is the polyol molecule that forms the backbone of glyceride lipids. This colorless and odorless liquid has a sweet flavor and a viscous consistency when separated out from plant oils. Hydrolysis is the process by which glycerin is made, in which the oils are subjected to intense pressure and temperature, at which point the ester bonds of the lipids break, and the glycerin is absorbed by the water present. Distillation then separates out the constituent parts, leaving pure glycerin as the final product!

Glycerin, also known as glycerol, has a number of unique qualities, which has made it a popular ingredient in the cosmetic and skincare industry, as well as in food production and alternative medicine fields. Although plant oils have been widely used since ancient times, the process for extracting glycerin wasn’t available until the 20th century. A significant amount of study and research has gone into the qualities and potential applications of glycerin. [1]


Many uses of glycerin have been identified over the years, thanks to its humectant (attracts moisture), emollient, anti-inflammatory, and sweetening qualities. The main industries vegetable glycerin finds use is in food production and the realm of cosmetics and skincare.

Close up of vegetable glycerin label on a bottle

Vegetable glycerin bottle Photo Credit: Shutterstock

Food Production

Due to the inherently sweet nature of glycerin, it is popular for use in food production, particularly as a sweetener in low-carbohydrate foods, in order to replace sugar. It also helps to thicken foods and balance moisture content, since it is a humectant substance. You will often find glycerin as an ingredient in baked goods, processed meats, ice cream, frozen foods, soybean products, condensed milk, condiments, and beverages. Unlike traditional sugar, glycerin does not lead to tooth decay, making it useful for sweet drinks and sodas. [2]


The more widespread use of glycerin, however, is in toiletry and skincare products, as well as natural medicines and therapeutic salves. Due to its humectant properties, any topical substance that contains glycerin will help to keep the skin hydrated, as it attracts moisture. Therefore, you often find this ingredient in lotions, moisturizers, shampoos, shaving creams, toothpaste, soap, deodorant, and makeup. It can be used in acne creams and salves, as well as body scrubs, aftershave lotions, and conditioners. It is used to lessen the appearance of scars, and may also appear as an ingredient in heart medications, suppositories, and cough medicines, among others. [3]

Vegetable Glycerin Benefits

There are many benefits of glycerin, including its ability to boost skin health, manage blood sugar, reduce constipation, improve energy levels, increase hydration, and eliminate inflammation.

  • Skin health: As mentioned above, glycerin can moisturize and soften the skin, due to its lubricant and emollient qualities, and also prevent dryness and irritation. It promotes wound healing on the skin and also establishes a protective barrier against damage from the wind, sun, and potential microbes to which you’re exposed. [4]
  • Skin absorption: The other critical element of glycerin when it comes to topical skin use is its ability to improve the absorption of other substances, as discussed in this article from the British Journal of Dermatology. When vegetable glycerin is included in other substances, its hygroscopic ability helps essential oils and other active ingredients be more effective on the skin, boosting the positive impact of any skin product. [5]
  • Manage blood sugar: In foods, glycerin is a good replacement for sugar, which can cause fluctuations in blood sugar and increase one’s risk of obesity and diabetes. [6]
  • Constipation: Studies have found that glycerin is a laxative substance, helping foods to move more easily through the gut. It is commonly used in enemas and is more effective and side-effect-free than many other standard laxatives if you’re feeling backed up or constipated. [7]
  • Hydration: Staying hydrated is not only critical to overall health, but also to performance and stamina. For example, dehydration can severely impact your ability to perform physical tasks or athletics, but glycerin can help to increase water retention and prolong hydration; it is also very rejuvenating for the body following an intense workout. [8]
  • Itching and Inflammation: It is well known that glycerin can form a defensive layer between your skin and the environment, making it good for conditions like eczema or acne. These issues often result in extreme itchiness, so glycerin can reduce the sensation of itchiness and thus prevent additional inflammation, as discussed in this article from Skin Pharmacology and Physiology. [9]
  • Antibacterial: The antibacterial qualities of glycerin on the skin mean that it can gently prevent future breakouts of pimples and acne, without the astringent effects of alcohol on the skin, nor any other harsh synthetic chemical. [10]

Side Effects

Despite its wide-ranging benefits, there are some side effects of vegetable glycerin that must be considered.

Stomach ailments: Though it is generally considered safe, you may experience some gastrointestinal symptoms, such as gas and diarrhea, when you consume it in supplemental quantities.

Allergic reactions: Furthermore, some people may be allergic to glycerin, or the plants from which the oil was initially derived, which could result in redness, irritation or other allergic reactions on the skin.

Other common symptoms include nausea, dizziness, and vomiting have also been reported in some people. The best practice is to speak with a doctor or medical professional, and then start with small quantities, whether you are consuming it in food or applying it to the skin. Protection Status
About the Author

John Staughton is a traveling writer, editor, publisher and photographer with English and Integrative Biology degrees from the University of Illinois in Champaign-Urbana (USA). He co-founded the literary journal, Sheriff Nottingham, and now serves as the Content Director for Stain’d Arts, a non-profit based in Denver, Colorado. On a perpetual journey towards the idea of home, he uses words to educate, inspire, uplift and evolve.

Rate this article
Average rating 0.0 out of 5.0 based on 0 user(s).